Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 2,885 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

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Issue DateTitleAuthor(s)
6127-May-2014Synthesis and cytotoxiticty studies of some new amino isoquinolin-5,8-dione and quinolin-5,8-dione derivativesAhmed B Abelwahab; Mohamed Shaaban; Mohamed A H Ismail; Abouzid, Khaled ; Atef G Hanna
622014Molecular modelling and synthesis of quinazoline-based compounds as potential antiproliferative agentsYassen, Asmaa Said Ali; Elshihawy, Hosam Eldin Abd Elhamed Ahmed; Said, Mohamed Mokhtar Amin; Abouzid, Khaled 
632014Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligandsOsman, Noha A.; Mahmoud, Amr H.; Klein, Christian D.; Allarà, Marco; Di Marzo, Vincenzo; Khaled A M Abouzid ; Abadi, Ashraf H.
64Oct-2013Molecular design and synthesis of HCV inhibitors based on thiazolone scaffoldAl-Ansary, Ghada H; Ismail, Mohamed A H; Abou El Ella, Dalal ; Eid, Sameh; Abouzid, Khaled 
65Jul-2013In silico design: extended molecular dynamic simulations of a new series of dually acting inhibitors against EGFR and HER2Ahmed, Marawan; Sadek, Maiada M; Abouzid, Khaled ; Wang, Feng
66Jun-2013Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypesTaher, Azza T; Kadry, Hanan H; Allarà, Marco; Di Marzo, Vincenzo; Abadi, Ashraf H; Abouzid, Khaled 
6715-May-2013Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activityLasheen, Deena S. ; Ismail, Mohamed A H; Ismail, Nasser S M; Eid, Sameh; Vleck, Susan; Glenn, Jeffrey S; Watts, Andrew G; Abouzid, Khaled ; Abou El Ella, Dalal 
68Mar-2013Design, synthesis and in vitro anti-proliferative activity of 4,6-quinazolinediamines as potent EGFR-TK inhibitorsMowafy, Samar; Farag, Nahla A; Abouzid, Khaled 
69Mar-2013Molecular design, synthesis and cell based HCV replicon assay of novel benzoxazole derivativesIsmail, M A H; Сиддик Адель Мухаммед ; Ismail, N S M; Abouzid, Khaled 
70Jan-20133-[(6-Arylamino)pyridazinylamino]benzoic acids: design, synthesis and in vitro evaluation of anticancer activityKhaled A M Abouzid ; Khalil, Nadia A; Ahmed, Eman M; Mohamed, Khaled Omar
712013Novel 2-thiopyrimidine derivatives as CDK2 inhibitors: molecular modeling, synthesis, and anti-tumor activity evaluationFathalla, OAM; Ismail, MAH; Anwar, MM; Abouzid, Khaled ; Ramadan, AAK
7220134-Substitutedphthalazines and phthalazinones: synthesis, characterization and beta-adrenergic blocking activityAbouzid, Khaled ; Khalil, NA; Ahmed, E.M. 
732013Synthesis and Biological Evaluation of New Heteroaryl Carboxylic Acid Derivatives as Anti-inflammatory-Analgesic AgentsAbouzid, Khaled ; Khalil, NA; Ahmed, E.M. ; Zaitone, SAB
741-Nov-2012Design, synthesis, and evaluation of anti-inflammatory and ulcerogenicity of novel pyridazinone derivativesKhalil, N. A.; Ahmed, E.M. ; Ahmed Esmat ; Al-Abd, A. M.; Khaled A M Abouzid 
75Nov-2012A highly selective structure-based virtual screening model of Palm I allosteric inhibitors of HCV Ns5b polymerase enzyme and its application in the discovery and optimization of new analoguesMahmoud, Amr H; Ismail, Mohamed A H; Abouzid, Khaled ; Abou El Ella, Dalal 
76Aug-2012Synthesis and anti-proliferative activity of substituted-anilinoquinazolines and its relation to EGFR inhibitionEl Ella, D A A; Saleh, K A; Hassan, M; Hamdy, N; El-Araby, M E; Abouzid, Khaled 
771-Apr-2012Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivativesIsmail, Mohamed A H; Abou El Ella, Dalal ; Khaled A M Abouzid ; Mahmoud, Amr H
782012Synthesis and evaluation of anti-proliferative activity of 1,4-disubstituted phthalazinesAbouzid, Khaled ; Khalil, NA; Ahmed, E.M. 
792012DESIGN, SYNTHESIS AND VIRTUAL SCREENING OF CERTAIN 2-PYRAZOLIN-5-ONE AND PYRAZOLIDINE-3, 5-DIONE DERIVATIVES AS POTENTIAL PPAR gamma AGONISTSIsmaila, MAH; El Ella, DAA; Abouzid, Khaled ; Jaballah, M
801-Nov-2011Baclofen ester and carbamate prodrug candidates: a simultaneous chromatographic assay, resolution optimized with DryLabHanafi, Rasha; Mosad, Salwa; Abouzid, Khaled ; Niess, Raimund; Spahn-Langguth, Hilde