Ahmed Esmat

ahmed.esmat@pharma.asu.edu.eg

Department of Pharmacology and Toxicology - Pharmacy
Interests: Bioactivation and mechanisms of chemically-induced toxicity, Oxidative stress-mediated cellular injury and protective antioxidant mechanisms, Susceptibility to drugs and chemical toxicity, Anti-inflammatory activity of natural and synthetic chemicals,
Internal ID: rp11912
  • 1,440 Scopus Citations
  • 349 PubMed Citations

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Full Name
Ahmed Esmat
 
 
 
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Biography
EDUCATION:
May 2002: Bachelor’s degree in Pharmaceutical Sciences, Ain-Shams University, Egypt, with the first rank over 366 students in my class.
September 2007: Master’s degree in Pharmaceutical Sciences (Pharmacology and Toxicology), Ain-Shams University, Egypt. Title: Evaluation of Nitrile(s) Toxicity on Rat Brain.
July 2008: International Computer Driving License (ICDL), Syllabus Version (4), endorsed by Ministry of Communications and Information Technology – Egypt, with the support of UNESCO.
August 2008: Test Of English as Foreign Language, internet Based Test (TOEFL iBT), score 101/120
October 2012: Ph.D. Pharmacology and Toxicology, Ain Shams University and The Ohio State University, Columbus, Ohio, USA (under the channel system and joint supervision scheme). Title: Developmental and Neurotoxicological Effects of Water Disinfection Byproduct(s) in Experimental Animals.

OCCUPATIONAL BACKGROUND:
September 2017 – present: Seconded Associate Professor, Department of Pharmacology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
January 2018 – present: Associate Professor, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
February 2017 – June 2017: (Part-time) Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Nahda University, Beni Suef, Egypt.
August 2015 – June 2016: (Part-time) Lecturer of Pharmacology and Toxicology, Technical Institute of Nursing, Egyptian Armed Forces, Egypt.
September 2013 – June 2015: (Part-time) Lecturer of Pharmacology and Toxicology, Faculty of Pharmacy, Misr International University (MIU), El-Obour city, Egypt.
November 2012 – December 2017: Lecturer, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
May 2012 – October 2012: Assistant lecturer, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
April 2011 – April 2012: Visiting Scholar, Center for Environmental and Smoking-Induced Diseases, Davis Heart & Lung Research Institute (DHLRI), Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.
November 2007 – March 2011: Assistant lecturer, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
January 2003 – October 2007: Demonstrator, Department of Pharmacology and Toxicology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

HONOURS:
March 2022 – present: Editor at “Egyptian Journal of Basic and Clinical Pharmacology”
March 2022: Contribution in The Multiple Mini Interview (MMI) 2022, division of Academic Counselling & Student Support Unit, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
November 16th, 2021: United States Patent; 11,174,233 B1 on the invention known as “Anticancer compounds having oxazolone derivation”.
November 13th, 2021: United States Patent; 11,180,458 B2 on the invention known as ““Anticancer compounds, pharmaceutical compositions thereof and a method of treating cancer”.
October 2021 - present: Reviewer Editor at Frontiers in Pharmacology -Ethnopharmacology.
October 2021: Abstract Reviewer for the international conference “Knowledge, Skill, & Ability in Pharmacy & Toxicology” (KSAPT) 2021; held by “Saudi Pharmaceutical Society”.
August 2021: Contribution in The Multiple Mini Interview (MMI) 2021, division of Academic Counselling & Student Support Unit, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
April 2015 – September 2017: Technical Manager of Experimental Advanced Pharmaceutical Research Unit “EAPRU”, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.
November 2013 – November 2017: Co-investigator in the project “Drug discovery and development research” ID: 5251, Type “Center of Excellence”, funded by STDF, Ministry of Scientific Research, Egypt.
April 2011 – April 2012: Scientific Mission to the Ohio State University, Columbus, Ohio, USA; awarded by the Egyptian Ministry of High Education and supported by the Egyptian Government according to the Channel System and Joint Supervision Scheme.

Reviewer at the following journals:
1. Arabian Journal of Chemistry
2. Archives of Medical research
3. Archives of Pharmaceutical Sciences - Ain Shams University
4. Bioorganic Chemistry
5. BMC Complementary Medicine and Therapies
6. Cellular signaling
7. Drug and Chemical Toxicology
8. Egyptian Journal of Basic and Applied Sciences
9. Egyptian Journal of Basic and Clinical Pharmacology
10. Frontiers in Pharmacology
11. Journal of Applied Toxicology
12. Journal of Ethnopharmacology
13. Journal of Functional Food
14. Journal of King Abdulaziz University-Medical Sciences
15. Life Sciences
16. Pharmacological Reports
17. Phytotherapy Research
18. Plants
19. Plos One
20. Reproductive Biology
21. Saudi Journal of biological sciences
22. Scientific Reports
23. The science of nature
24. Toxicology and Industrial Health

Contribution in “Establishment of an Internal Quality Assurance System” as one of the “Quality Assurance and Accreditation Projects (QAAP) of higher education in Egypt (2006-2007), performing the following roles:
1. Preparing all course specifications and reports belonging to Pharmacology department, Faculty of Pharmacy, Ain Shams University
2. Preparing the specification and report of the educational program “Bachelor of Pharmaceutical Sciences”

Contribution in “Continuous Improvement for Qualification & Accreditation Project (CIQAP) of higher education in Egypt (2008-2010), in Educational Programs Criterion that involved annual preparation and revision of all specifications and reports concerning all under- and postgraduate programs:
1. Bachelor of Pharmaceutical sciences program
2. Bachelor of Pharmaceutical sciences and drug design program
3. Diploma of Clinical Pharmacy
4. Master programs of all Faculty departments
5. Ph.D. programs of all Faculty departments

April - September 2017: Member of the scientific committee responsible for evaluation of preclinical studies for pharmaceutical products in National Organization for Drug and Control Research, Egypt (NODCAR).

Publications

Results 1-20 of 45 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
121-Jul-2022Novel Nanoconjugate of Apamin and Ceftriaxone for Management of Diabetic WoundsAlamoudi, Abdullah A; Alharbi, Awaad S; Abdel-Naim, Ashraf B; Badr-Eldin, Shaimaa M; Awan, Zuhier A; Okbazghi, Solomon Z; Ahmed, Osama A A; Alhakamy, Nabil A; Fahmy, Usama A; Ahmed Esmat 
221-Mar-2022Evaluation of lyophilized royal jelly and garlic extract emulgels using a murine model infected with methicillin-resistant Staphylococcus aureusEl-Gayar, Mona H; Ishak, Rania A H; Ahmed Esmat ; Aboulwafa, Mohammad M ; Aboshanab, Khaled 
318-Mar-2022Lycorine Ameliorates Thioacetamide-Induced Hepatic Fibrosis in Rats: Emphasis on Antioxidant, Anti-Inflammatory, and STAT3 Inhibition EffectsAlkreathy, Huda Mohammed; Ahmed Esmat 
4Nov-2021Auraptene nanoparticles ameliorate testosterone-induced benign prostatic hyperplasia in rats: Emphasis on antioxidant, anti-inflammatory, proapoptotic and PPARs activation effectsAlmukadi, Haifa; Eid, Basma G; Shaik, Rasheed A; Abdel-Naim, Ashraf B; Ahmed Esmat 
5Nov-2021Naringin treatment improved main clozapine-induced adverse effects in rats; emphasis on weight gain, metabolic abnormalities, and agranulocytosisMenze, Esther ; Tadros, Mariane G; El-Demerdash, Ebtehal; George, Mina Y. ; Ahmed Esmat 
61-Jul-2021Protective and therapeutic effects of the flavonoid “pinocembrin” in indomethacin-induced acute gastric ulcer in rats: impact of anti-oxidant, anti-inflammatory, and anti-apoptotic mechanismsEl-Demerdash, Aya A.; Ahmed Esmat ; Tadros, Mariane G.; Elsherbiny, Doaa A.; Menze, Esther 
713-Apr-2021Carvedilol Exerts Neuroprotective Effect on Rat Model of Diabetic NeuropathyMagadmi, Rania M.; Alsulaimani, Mujahid A.; Al-Rafiah, Aziza R.; Ahmad, Muhammad Saeed; Ahmed Esmat 
81-Jan-2021Wound healing activity of opuntia ficus-indica fixed oil formulated in a self-nanoemulsifying formulationKoshak, Abdulrahman E.; Algandaby, Mardi M.; Mujallid, Mohammad I.; Abdel-Naim, Ashraf B.; Alhakamy, Nabil A.; Fahmy, Usama A.; Alfarsi, Anas; Badr-Eldin, Shaimaa M.; Neamatallah, Thikryat; Nasrullah, Mohammed Z.; Abdallah, Hossam M.; Ahmed Esmat 
91-Jan-2021The Neuroprotective Effect of Carvedilol on Diabetic Neuropathy: An in Vitro StudyMagadmi, Rania M.; Alsulaimani, Mujahid A.; Al-Rafiah, Aziza Rashed; Ahmed Esmat 
101-Oct-2020Bisoprolol responses (PK/PD) in hypertensive patients: A cytochrome P450 (CYP) 2D6 targeted polymorphism studyMohammed Alkreathy, Huda; Mohammed Eid Alsayyid, Khlood; Alaama, Jumana Y.; Al Ghalayini, Kamal; Karim, Shahid; Ahmed Esmat ; Damanhouri, Zoheir A.
111-Aug-2020Aged garlic extract potentiates doxorubicin cytotoxicity in human breast cancer cellsAlkreathy, Huda Mohammed; AlShehri, Noura Farraj; Kamel, Fatemah Omer; Alghamdi, Ahmed Khalaf; Ahmed Esmat ; Karim, Shahid
121-Jul-2020Anti-inflammatory activity of the lipophilic metabolites from Scolymus hispanicus LKandil, Zeinab A.; Ahmed Esmat ; El-Din, Reham Salah; Ezzat, Shahira M.
131-Jun-2020Anti-inflammatory Activity and Chemical Characterisation of Opuntia ficus-indica Seed Oil Cultivated in Saudi ArabiaKoshak, Abdulrahman E.; Abdallah, Hossam M.; Ahmed Esmat ; Rateb, Mostafa E.
1415-May-2020Potential therapeutic antipsychotic effects of Naringin against ketamine-induced deficits in rats: Involvement of Akt/GSK-3β and Wnt/β-catenin signaling pathwaysAhmed Esmat ; Tadros, Mariane G.; Menze, Esther ; El-Demerdash E ; George, Mina Y. 
152020Tetramethylpyrazine ameliorates indomethacin-induced gastric ulcer in rats: Impact on oxidative, inflammatory, and angiogenic machineriesAhmed Esmat 
161-Oct-2018Anti-inflammatory activity of Kleinia odoraShehata, Ibrahim A.; El-harshany, Essam; Abdallah, Hossam M.; Ahmed Esmat ; Abdel-sattar, Essam A.
171-Jul-2018Role of prostaglandiin H synthase in activation of acrylonitrile to cyanideAl-Abbasi, Fahad Ahmed; Ahmed Esmat ; MohamAdin, Ahmed Mohamed; Abdel-Naim, Ashraf Bahyeldeen
181-Apr-2018Cucurbitacin-B attenuates CCl <inf>4</inf> -induced hepatic fibrosis in mice through inhibition of STAT-3Sallam, Alaliaa M.; Ahmed Esmat ; Abdel-Naim, Ashraf B.
191-Mar-2018Thiotagetin B and tagetannins A and B, new acetylenic thiophene and digalloyl glucose derivatives from Tagetes minuta and evaluation of their in vitro antioxidative and anti-inflammatory activityIbrahim, Sabrin R.M.; Abdallah, Hossam M.; El-Halawany, Ali M.; Esmat, Ahmed ; Mohamed, Gamal A.
201-Mar-2018High resolution UPLC-MS/MS profiling of polyphenolics in the methanol extract of Syzygium samarangense leaves and its hepatoprotective activity in rats with CCl<inf>4</inf>-induced hepatic damageSobeh, Mansour; Youssef, Fadia S.; Ahmed Esmat ; Petruk, Ganna; El-Khatib, Ahmed H.; Monti, Daria Maria; Ashour, Mohamed L. ; Wink, Michael