Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 2,885 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Refined By:
Author:  Lasheen, Deena

Results 1-20 of 20 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
1Dec-2022Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling studyElmenier, Fatma M; Lasheen, Deena ; Abouzid, Khaled 
2Dec-2022Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cellsAbdelhafiz, Abeer H A; Serya, Rabah A T; Lasheen, Deena S. ; Wang, Nessa; Sobeh, Mansour; Wink, Michael; Abouzid, Khaled 
38-Mar-2022Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluationMansour, Mai A; Oraby, Mamdouh A; Muhammad, Zeinab A; Lasheen, Deena ; Gaber, Hatem M; Khaled A M Abouzid 
426-Aug-2020Elaborating piperazinyl-furopyrimidine based scaffolds as phosphoinositol-3-kinase enzyme alpha (PI3Kα) inhibitors to combat pancreatic cancerMansour, Mai A; Lasheen, Deena S. ; Gaber, Hatem M; Khaled A M Abouzid 
5Aug-2020Scaffold hopping and redesign approaches for quinazoline based urea derivatives as potent VEGFR-2 inhibitorsHadi, Soha R Abd El; Soliman, Dalia H; Elrazaz, Eman ; Khaled A M Abouzid ; Lasheen, Deena S. 
61-Dec-2019Phosphatidylinositol 3 kinase (PI3K) inhibitors as new weapon to combat cancerElmenier, Fatma M; Lasheen, Deena S. ; Khaled A M Abouzid 
7Aug-20193D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluationSobhy, Mahitab K; Mowafy, Samar; Lasheen, Deena S. ; Farag, Nahla A; Khaled A M Abouzid 
8Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
9Sep-2018Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted TherapyAdel, Mai; Serya, Rabah A T; Lasheen, Deena S. ; Abouzid, Khaled 
10Sep-2018Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancerHesham, Heba M; Lasheen, Deena S. ; Khaled A M Abouzid 
1115-Jul-2018Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinomaShahin, Mai I; Roy, Joyeeta; Hanafi, Maha; Wang, Dongyao; Luesakul, Urarika; Chai, Yifeng; Muangsin, Nongnuj; Lasheen, Deena S. ; Neamati, Nouri; Khaled A M Abouzid ; Abou El Ella, Dalal 
1215-Jul-2018Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitorsMilik, Sandra N; Abdel-Aziz, Amal Kamal; Serya, Rabah ; Minucci, Saverio; Lasheen, Deena S. ; Khaled A M Abouzid 
131-Jun-2018Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agentsFawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled 
142018Design, synthesis, molecular docking study, and biological evaluation of salicylaldimine derivatives as potential histone deacetylases inhibitors (HDACi) and anticancer agentsHesham, Heba; Lasheen, Deena S. ; Abouzid, Khaled 
156-Jul-2017Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2)Mehanna, Wesam E; Lu, Tiangong; Debnath, Bikash; Lasheen, Deena S. ; Serya, Rabah A T; Abouzid, Khaled ; Neamati, Nouri
16Nov-2016Design and Synthesis of 4-Anilinothieno[2,3-d]pyrimidine-Based Compounds as Dual EGFR/HER-2 InhibitorsAbd El Hadi, Soha R; Lasheen, Deena S. ; Hassan, Mahmoud A; Khaled A M Abouzid 
1715-Aug-2016Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivativesMowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S. ; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled 
18Aug-2016Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical ProfilesHossam, Monia; Lasheen, Deena S. ; Abouzid, Khaled 
1915-Apr-2016Discovery of Potent VEGFR-2 Inhibitors based on Furopyrimidine and Thienopyrimidne Scaffolds as Cancer Targeting AgentsAziz, Marwa A; Serya, Rabah A T; Lasheen, Deena S. ; Abdel-Aziz, Amal Kamal ; Mansour, Ahmed M; Ahmed Esmat ; Singab A. ; Khaled A M Abouzid 
2015-May-2013Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activityLasheen, Deena S. ; Ismail, Mohamed A H; Ismail, Nasser S M; Eid, Sameh; Vleck, Susan; Glenn, Jeffrey S; Watts, Andrew G; Abouzid, Khaled ; Abou El Ella, Dalal