Lasheen, Deena S.

deenalasheen@pharma.asu.edu.eg

Interests: Medicinal Chemistry and Drug Discovery,
Internal ID: rp12112
  • 720 Scopus Citations
  • 189 PubMed Citations

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Full Name
Lasheen, Deena S.
 
Scopus Author ID
 

Publications

Refined By:
Type:  Journal Article
Date Issued:  [2010 TO 2019]

Results 1-20 of 20 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
11-Dec-2019Phosphatidylinositol 3 kinase (PI3K) inhibitors as new weapon to combat cancerElmenier, Fatma M; Lasheen, Deena S. ; Khaled A M Abouzid 
2Dec-2019Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibitionElmeligie, Salwa; Aboul-Magd, Asmaa M; Lasheen, Deena S. ; Ibrahim, Tamer M; Abdelghany, Tamer M; Khojah, Sohair M
3Aug-20193D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluationSobhy, Mahitab K; Mowafy, Samar; Lasheen, Deena S. ; Farag, Nahla A; Khaled A M Abouzid 
42019Apoptosis in cancer: from pathogenesis to discovery of advanced selective Bcl-2 family inhibitorsAbbas, Samaa; Abdou, Nermin; Lasheen, Deena S. ; Abou El Ella, Dalal 
5Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
6Sep-2018Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted TherapyAdel, Mai; Serya, Rabah A T; Lasheen, Deena S. ; Abouzid, Khaled 
7Sep-2018Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancerHesham, Heba M; Lasheen, Deena S. ; Khaled A M Abouzid 
815-Jul-2018Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinomaShahin, Mai I; Roy, Joyeeta; Hanafi, Maha; Wang, Dongyao; Luesakul, Urarika; Chai, Yifeng; Muangsin, Nongnuj; Lasheen, Deena S. ; Neamati, Nouri; Khaled A M Abouzid ; Abou El Ella, Dalal 
915-Jul-2018Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitorsMilik, Sandra N; Abdel-Aziz, Amal Kamal; Serya, Rabah ; Minucci, Saverio; Lasheen, Deena S. ; Khaled A M Abouzid 
101-Jun-2018Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agentsFawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled 
112018Imidazo[2',1':2,3]thiazolo[4,5-d]pyridazinone as a new scaffold of DHFR inhibitors: Synthesis, biological evaluation and molecular modeling studyEwida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I
122018Design, synthesis, molecular docking study, and biological evaluation of salicylaldimine derivatives as potential histone deacetylases inhibitors (HDACi) and anticancer agentsHesham, Heba; Lasheen, Deena S. ; Abouzid, Khaled 
13Oct-2017Thiazolo[4,5-d]pyridazine analogues as a new class of dihydrofolate reductase (DHFR) inhibitors: Synthesis, biological evaluation and molecular modeling studyEwida, Menna A; Abou El Ella, Dalal ; Lasheen, Deena S. ; Ewida, Heba A; El-Gazzar, Yomna I; El-Subbagh, Hussein I
146-Jul-2017Synthesis, ADMET Properties, and Biological Evaluation of Benzothiazole Compounds Targeting Chemokine Receptor 2 (CXCR2)Mehanna, Wesam E; Lu, Tiangong; Debnath, Bikash; Lasheen, Deena S. ; Serya, Rabah A T; Abouzid, Khaled ; Neamati, Nouri
15Nov-2016Design and Synthesis of 4-Anilinothieno[2,3-d]pyrimidine-Based Compounds as Dual EGFR/HER-2 InhibitorsAbd El Hadi, Soha R; Lasheen, Deena S. ; Hassan, Mahmoud A; Khaled A M Abouzid 
1615-Aug-2016Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivativesMowafy, Samar; Galanis, A; Doctor, Zainab M; Paranal, Raymond M; Lasheen, Deena S. ; Farag, Nahla A; Jänne, Pasi A; Abouzid, Khaled 
17Aug-2016Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical ProfilesHossam, Monia; Lasheen, Deena S. ; Abouzid, Khaled 
1815-Apr-2016Discovery of Potent VEGFR-2 Inhibitors based on Furopyrimidine and Thienopyrimidne Scaffolds as Cancer Targeting AgentsAziz, Marwa A; Serya, Rabah A T; Lasheen, Deena S. ; Abdel-Aziz, Amal Kamal ; Mansour, Ahmed M; Ahmed Esmat ; Singab A. ; Khaled A M Abouzid 
191-Aug-2015Design and synthesis of benzothiazole-6-sulfonamides acting as highly potent inhibitors of carbonic anhydrase isoforms I, II, IX and XIIIbrahim, Diaa A; Lasheen, Deena S. ; Zaky, Maysoun Y; Ibrahim, Amany W; Vullo, Daniela; Ceruso, Mariangela; Supuran, Claudiu T; Abou El Ella, Dalal 
2015-May-2013Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activityLasheen, Deena S. ; Ismail, Mohamed A H; Ismail, Nasser S M; Eid, Sameh; Vleck, Susan; Glenn, Jeffrey S; Watts, Andrew G; Abouzid, Khaled ; Abou El Ella, Dalal