Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors
Abouzid, Khaled; Khalil, NA; Ahmed, E.M.; El-Latif, HAA; El-Araby, ME;
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| Title | Structure-based molecular design, synthesis, and in vivo anti-inflammatory activity of pyridazinone derivatives as nonclassic COX-2 inhibitors | Authors | Abouzid, Khaled ; Khalil, NA; Ahmed, E.M. ; El-Latif, HAA; El-Araby, ME | Keywords | Quinoxaline;Pyridazinone;Anti-inflammatory;Molecular design;Synthesis;SELECTIVE CYCLOOXYGENASE-2 INHIBITORS;COLORECTAL-CANCER PREVENTION;BIOLOGICAL EVALUATION;AGENTS;EXPRESSION;SERIES;DRUGS | Issue Date | 2010 | Publisher | SPRINGER BIRKHAUSER | Journal | Medicinal Chemistry Research | Volume | 19 | Start page | 629 | End page | 642 | ISSN | 1054-2523 | DOI | 10.1007/s00044-009-9218-4 | Web of science ID | WOS:000280557700002 |
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