New fluorobenzamidine exerts antitumor activity against breast cancer in mice via pro-apoptotic activity
Saleh, AbdelRahman B; Hassan, Nagwa H.; Ismail, Mohamed A; El-Sayed, Wael;
Abstract
Breast cancer is one of the leading causes of cancer-related morbidities. The present study aimed to evaluate the efficacy of bithiophene-fluorobenzamidine (BFB) against breast cancer induced by 7,12-dimethylbenz(a)anthracene (DMBA) in female Swiss mice and reveal the underlining mechanisms.
Other data
| Title | New fluorobenzamidine exerts antitumor activity against breast cancer in mice via pro-apoptotic activity | Authors | Saleh, AbdelRahman B; Hassan, Nagwa H. ; Ismail, Mohamed A ; El-Sayed, Wael | Keywords | Apoptosis;Bithiophene;CDK1;ESR;Tamoxifen | Issue Date | 15-Sep-2022 | Publisher | SPRINGER | Journal | Discover Oncology | Volume | 13 | Start page | 88 | ISSN | 1868-8497 | DOI | 10.1007/s12672-022-00554-6 | PubMed ID | 36107265 | Scopus ID | 2-s2.0-85138181727 | Web of science ID | WOS:000854765600001 |
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