A combined treatment of curcumin, piperine, and taurine alters the circulating levels of IL-10 and miR-21 in hepatocellular carcinoma patients: a pilot study

Hatab, Hala M; Abdel Hamid, Fatma F; Soliman, Ahmed; Al-Shafie, Tamer A; Ismail, Yahia M; El-Houseini, Motawa E;

Abstract


Investigating and evaluating possible alternative therapeutic strategies to control hepatocellular carcinoma (HCC) is a critical need because of its high prevalence and being one of the most lethal cancers. Curcumin and taurine showed potent anti-tumor activities in pre-clinical and clinical studies by targeting multiple pathways. Thus, this study was designed to assess the effect of a combined treatment consisted of curcumin, piperine, and taurine on circulating levels of interleukin-10 (IL-10), and microRNAs miR-141 and miR-21.


Other data

Title A combined treatment of curcumin, piperine, and taurine alters the circulating levels of IL-10 and miR-21 in hepatocellular carcinoma patients: a pilot study
Authors Hatab, Hala M; Abdel Hamid, Fatma F; Soliman, Ahmed ; Al-Shafie, Tamer A; Ismail, Yahia M; El-Houseini, Motawa E
Issue Date Aug-2019
Publisher PIONEER BIOSCIENCE PUBL CO
Journal Journal of gastrointestinal oncology 
DOI 766-776
4
776
10
10.21037/jgo.2019.03.07
PubMed ID 31392057
Web of science ID WOS:000474645400019

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