Abouzid, Khaled

khaled.abouzid@pharma.asu.edu.eg

Department of Pharmaceutical Chemistry - Pharmacy
Interests: Anticancer drug discovery, design and synthesis, Antimicrobial,
Internal ID: rp12178
  • 2,885 Scopus Citations
  • 592 PubMed Citations

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Full Name
Abouzid, Khaled
 
 
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Biography
Dr. Khaled Abouzid is a Professor of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Prominent Scholar in Drug Discovery, Co-founding Director of Center of Drug Discovery and Development Research ASU He was nominated as the Acting Dean of the Faculty of Pharmacy, University of Sadat City from 8-2018 to 8-2022. He is currently a member of national pharmaceutical chemistry promotion committee
Dr. Abouzid’s research is directed towards drug discovery of bioactive small molecules with special emphasis on cannabinoids, targeted anticancer, anti-inflammatory, anti-viral anti-microbial agents and enzyme inhibitors. He has published over 150 research papers, two books and filed 14 patents in medicinal chemistry. He has Scopus H index of 28. He has supervised over 100 Master and PhD students in 7 universities. Dr Abouzid has research collaborations with German, British, Swedish, Canadian and US universities. He has also organized and presided over 34 international symposia and conferences.
Dr. Abouzid obtained his B.Sc. degree in Pharmaceutical Sciences from Cairo University in 1985, and his PhD. joint degree in Organic Chemistry from the Faculty of Pharmacy, Cairo University and School of Pharmacy University of Connecticut, USA.
Dr. Abouzid started his career in 1995 as a lecturer of Organic Chemistry at Cairo University, Faculty of Pharmacy. In 2001, he moved to the Department of Pharmaceutical Chemistry, Ain Shams University, and was promoted to Associate Professor in 2003. He did postdoctoral work with Professor Jochen Lehman of the Friedrich-Schiller-Universität Jena, Germany.

Publications

Results 81-100 of 133 (Search time: 0.0 seconds).

Issue DateTitleAuthor(s)
8115-Dec-2017How to train your inhibitor: Design strategies to overcome resistance to Epidermal Growth Factor Receptor inhibitorsMilik, Sandra N; Lasheen, Deena S; Serya, Rabah ; Abouzid, Khaled A M; Khaled A M Abouzid 
822018Acrylamide moiety, a Valuable Fragment in Medicinal Chemistry: Insight into Synthetic Methodologies, Chemical Reactivity and Spectrum of Biological Activities of Acrylamide DerivativesElgiushy, Hossam; Hammad, Sherif; Hassan, Ashraf; Aboutaleb, Nageh; Abouzid, Khaled 
832018Design, synthesis, molecular docking study, and biological evaluation of salicylaldimine derivatives as potential histone deacetylases inhibitors (HDACi) and anticancer agentsHesham, Heba; Lasheen, Deena S. ; Abouzid, Khaled 
8425-May-2018Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogensElAwamy, Moustafa; Mohammad, Haroon; Hussien, Abdelrahman; Abutaleb, Nader S; Hagras, Mohamed; Serya, Rabah ; Taher, Azza T; Seleem, Mohamed N; Mayhoub, Abdelrahman S; Khaled A M Abouzid 
851-Jun-2018Design, synthesis and 3D QSAR based pharmacophore study of novel imatinib analogs as antitumor-apoptotic agentsFawzy, Iten M; Youssef, Khairia M; Lasheen, Deena S. ; Ismail, Nasser Sm; Abouzid, Khaled 
8615-Jul-2018Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinomaShahin, Mai I; Roy, Joyeeta; Hanafi, Maha; Wang, Dongyao; Luesakul, Urarika; Chai, Yifeng; Muangsin, Nongnuj; Lasheen, Deena S. ; Neamati, Nouri; Khaled A M Abouzid ; Abou El Ella, Dalal 
8715-Jul-2018Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitorsMilik, Sandra N; Abdel-Aziz, Amal Kamal; Serya, Rabah ; Minucci, Saverio; Lasheen, Deena S. ; Khaled A M Abouzid 
88Sep-2018Pyrrolopyrimidine, A Multifaceted Scaffold in Cancer Targeted TherapyAdel, Mai; Serya, Rabah A T; Lasheen, Deena S. ; Abouzid, Khaled 
89Sep-2018Chimeric HDAC inhibitors: Comprehensive review on the HDAC-based strategies developed to combat cancerHesham, Heba M; Lasheen, Deena S. ; Khaled A M Abouzid 
9013-Nov-2018Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axisGe, Xin; Pan, Min-Hong; Wang, Lin; Li, Wei; Jiang, Chengfei; He, Jun; Abouzid, Khaled ; Liu, Ling-Zhi; Shi, Zhumei; Jiang, Bing-Hua
91Dec-2018Identification of new pyrrolo[2,3-d]pyrimidines as potent VEGFR-2 tyrosine kinase inhibitors: Design, synthesis, biological evaluation and molecular modelingAdel, Mai; Serya, Rabah ; Lasheen, Deena S. ; Khaled A M Abouzid 
922019Identification of novel pyrazole and benzimidazole based derivatives as PBP2a inhibitors: Design, synthesis, and biological evaluationShalaby, Menna-Allah; Dokla, Eman ; Serya, Rabah ; Abouzid, Khaled 
932019Design, synthesis and molecular docking of novel pyrazolo[1,5-a][1,3,5]triazine derivatives as CDK2 inhibitorsOudah, Khulood H; Najm, Mazin A A; Samir, Nermin; Serya, Rabah ; Khaled A M Abouzid 
942019Design, synthesis, biological evaluation and dynamics simulation of indazole derivatives with antiangiogenic and antiproliferative anticancer activityElsayed, Nevine M Y; Serya, Rabah ; Tolba, Mai ; Ahmed, Marawan; Barakat, Khaled; Abou El Ella, Dalal ; Khaled A M Abouzid 
95Mar-2019Design, synthesis and molecular modeling study of certain VEGFR-2 inhibitors based on thienopyrimidne scaffold as cancer targeting agentsGhith, Amna; Youssef, Khairia M; Ismail, Nasser S M; Abouzid, Khaled 
9625-Mar-2019Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic InducersEl Newahie, Aliya M S; Nissan, Yassin M; Ismail, Nasser S M; Abou El Ella, Dalal ; Khojah, Sohair M; Abouzid, Khaled 
97Aug-20193D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluationSobhy, Mahitab K; Mowafy, Samar; Lasheen, Deena S. ; Farag, Nahla A; Khaled A M Abouzid 
9815-Nov-20191,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLCDokla, Eman ; Fang, Chun Sheng; Chen, Ching S.; Abouzid, Khaled 
99Dec-2019Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activitiesJaballah, Maiy Y; Serya, Rabah ; Saad, Nasser; Khojah, Sohair M; Ahmed, Marawan; Barakat, Khaled; Khaled A M Abouzid 
1001-Dec-2019Phosphatidylinositol 3 kinase (PI3K) inhibitors as new weapon to combat cancerElmenier, Fatma M; Lasheen, Deena S. ; Khaled A M Abouzid